Clinical and Laboratory Observation of Brucellosis: Ardahan


Abstract views: 119 / PDF downloads: 41

Authors

DOI:

https://doi.org/10.5281/zenodo.8406548

Keywords:

Ardahan, Brucellosis, Eastern Anatolia, complication

Abstract

Brucellosis is a major public health problem due to its non-specific symptoms and variable clinic. It was aimed to evaluate the clinical case of 11 infected individuals who were diagnosed with brucellosis and admitted to the hospital in the Eastern Anatolia Region (Ardahan Province), where this zoonotic infection is endemic. This is a retrospective study of patients admitted to Ardahan Göle State Hospital whose medical records and clinical findings were reviewed until October 2023 (Approval of Ardahan University Scientific Research and Publication Ethics Committee (Protocol No: 2022-2ÖNP-0115, Approval Date: 04.01.2023- Number: E-67796128-000-2200042053). The data included in the study were obtained from 64% women and 36% men. Analyses showed a significant decrease in hct, albumin and hemoglobin levels (p<0.001; p<0.05; p<0.01, respectively). In addition, statistically significant increases were found in wbc, crp and total Bilirubin levels (respectively, p<0.01; p<0.001; p<0.01). The clinical symptoms of this infection, which can affect any organ and system, may vary. Therefore, monitoring of variable findings, especially in endemic regions, should bring brucellosis to mind. Although there is no culture in the diagnosis, the need for serological tests is important.

References

Araj, G.F. 2010. Update on laboratory diagnosis of human brucellosis. International Journal of Antimicrobial Agents, 36: 12-17.

Aygen, B., Doğanay, M., Sümerkan, B., Yildiz, O., Kayabaş, Ü. 2002. Clinical manifestations, complications and treatment of brucellosis: a retrospective evaluation of 480 patients. Medecine et Maladies Infectieuses, 32(9): 485-493.

Doğu, G.G., Soysal, Ö., Yıldırım, O., Eralp, B. 2003. Brusellozis. Göztepe Tıp Dergisi, 18(4): 249-250.

El-Sayed, A., Awad, W. 2018. Brucellosis: Evolution and expected comeback. International Journal of Veterinary Science and Medicine, 6(Suppl): 31-35.

Herran Ramirez, O. L., Azevedo Santos, H., Jaramillo Delgado, I. L., da Costa Angelo, I. 2020. Seroepidemiology of bovine brucellosis in Colombia's preeminent dairy region, and its potential public health impact. Brazilian Journal of Microbiology, 51(4): 2133-2143.

Kaden, R., Ferrari, S., Jinnerot, T., Lindberg, M., Wahab, T., Lavander, M. 2018. Brucella abortus: determination of survival times and evaluation of methods for detection in several matrices. BMC Infectious Diseases, 18(1): 259.

Kış, T.T., Mehmet, K., Şükran, K. 2020. 111 Bruselloz olgusunun etyoloji, klinik seyir ve komplikasyonlarının değerlendirilmesi; bir retrospektif çalışma. Mersin Üniversitesi Sağlık Bilimleri Dergisi, 13(3): 339-347.

Liu, Z., Wang, M., Tian, Y., Li, Z., Gao, L., Li, Z. 2022. A systematic analysis of and recommendations for public health events involving brucellosis from 2006 to 2019 in China. Annals of Medicine, 54(1): 1859-1866.

Okur, M., Erbey, F., Bektaş, M. S., Kaya, A., Doğan, M., Acar, M. N., & Uzun, H. 2012. Retrospective clinical and laboratory evaluation of children with brucellosis. Pediatrics International, 54(2): 215-218.

Pappas, G. 2010. The changing Brucella ecology: novel reservoirs, new threats. International Journal of Antimicrobial Agents, 36 Suppl 1: 8-11.

Pinn-Woodcock, T., Frye, E., Guarino, C., Franklin-Guild, R., Newman, A. P., Bennett, J., Goodrich, E. L. 2023. A one-health review on brucellosis in the United States. Journals-American Veterinary Medical Association, 261(4): 451-462.

Prasad, A. K. 2015. Brucellosis in Nepal: A Potential Threat To Public Health Professionals. JMS SKIMS, 18(2): 138-149.

Rahil, A.I., Othman, M., Ibrahim, W., Mohamed, M.Y. 2014. Brucellosis in Qatar: a retrospective cohort study. Qatar Medical Journal, (1): 4.

Rhyan, J.C., Nol, P., Quance, C., Gertonson, A., Belfrage, J., Harris, L., Straka, K., Robbe-Austerman, S. 2013. Transmission of brucellosis from elk to cattle and bison, Greater Yellowstone area, U.S.A., 2002-2012. Emerging Infectious Diseases, 19(12): 1992-1995.

Shrestha, S., Karn, M., Regmi, S. M., Nagila, A., & Pahari, S. 2022. Clinical profile and biochemical abnormalities in brucellosis: a cross-sectional study. Annals of Medicine and Surgery, 79: 103922.

Tansel, Ö., Yavuz, M., Kuloğlu, F., Akata, F. 2003. Trakya Üniversitesi Hastanesi'ne başvuran 40 bruselloz olgusunun değerlendirilmesi. İnfeksiyon Dergisi, 17(1): 1-4.

Published

2023-10-07

How to Cite

YAŞAR, Ümit. (2023). Clinical and Laboratory Observation of Brucellosis: Ardahan. MAS Journal of Applied Sciences, 8(4), 807–812. https://doi.org/10.5281/zenodo.8406548

Issue

Section

Articles

Most read articles by the same author(s)